CFTR protein
Task 1
Identification of motifs
Searching for protein motifs
Reading the results page
Midway summary
Examining the effect of a CFTR gene mutation on structural and functional motifs in the protein
Summary of the tool – Prosite
Task 2
Designing PCR primers
The characteristics of the primers
Reading the results page
Defining Limitations
Using a specific pre-determined primer sequence
Analysis of PCR results
Summary of the tool – Primer3+
Module Summary
References and Further Reading
IPNS protein
The three-dimensional (3-D) structure of the IPNS enzyme
First steps
Secondary structure display
Display of the atomic spatial structure (Van der Waals interactions)
Displaying the structure of the active site
The substrate binding to the active site
Summary of the task
AFP protein
Task description
Task 1: The structure of the antifreeze proteins
Task 1: Part1
Task 1: Part2
Task 1: Part3
Task 1: Part4
Task 2: Analysis of the structure of the MpAFP protein’s subunit A
Task 2: Part1
Task 2: Part2
Task 2: Part3
Summary of the study
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CFTR PROTEIN
Task no. 1
Task no. 2
Module Summary
References and Further Reading
IPNS PROTEIN
The three-dimensional (3-D) structure of the IPNS enzyme
First steps
Secondary structure display
Display of the atomic spatial structure (Van der Waals interactions)
Displaying the structure of the active site
The substrate binding to the active site
Summary of the task
AFP PROTEIN
Description of the task (Jmol)
Task 1: The structure of the antifreeze proteins
Task 2: Analysis of the structure of the MpAFP protein’s subunit A-Part1
Summary of the study
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