{"id":496,"date":"2016-11-27T12:11:17","date_gmt":"2016-11-27T10:11:17","guid":{"rendered":"https:\/\/stwww1.weizmann.ac.il\/cell\/?p=496"},"modified":"2019-04-18T14:50:35","modified_gmt":"2019-04-18T11:50:35","slug":"%d7%94%d7%a7%d7%a9%d7%a8-%d7%91%d7%99%d7%9f-%d7%97%d7%95%d7%98%d7%99-%d7%9b%d7%99%d7%a9%d7%95%d7%a8-%d7%9c%d7%9b%d7%a8%d7%95%d7%9e%d7%95%d7%96%d7%95%d7%9e%d7%99%d7%9d","status":"publish","type":"post","link":"https:\/\/stwww1.weizmann.ac.il\/cell\/?p=496","title":{"rendered":"\u05d4\u05e7\u05e9\u05e8 \u05d1\u05d9\u05df \u05d7\u05d5\u05d8\u05d9 \u05db\u05d9\u05e9\u05d5\u05e8 \u05dc\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05de\u05d9\u05dd"},"content":{"rendered":"<p>\u05d0\u05d9\u05da \u05d1\u05db\u05dc\u05dc \u05e0\u05e7\u05e9\u05e8\u05d9\u05dd \u05d7\u05d5\u05d8\u05d9 \u05d4\u05db\u05d9\u05e9\u05d5\u05e8 \u05dc\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05de\u05d9\u05dd? \u05d1\u05d0\u05d6\u05d5\u05e8 \u05d4<a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?page_id=44#82\">\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8<\/a> \u05e0\u05de\u05e6\u05d0\u05d9\u05dd <a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?page_id=44#24\">\u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd<\/a> \u05d9\u05d9\u05d7\u05d5\u05d3\u05d9\u05d9\u05dd \u05e9\u05e0\u05e7\u05e9\u05e8\u05d9\u05dd \u05d1\u05de\u05d9\u05d5\u05d7\u05d3 \u05dc\u05d0\u05d6\u05d5\u05e8 \u05d6\u05d4 \u05d1<a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?page_id=44#39\">\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05dd<\/a>. \u05d1\u05e9\u05dc\u05d1\u05d9\u05dd \u05e9\u05d1\u05d4\u05dd \u05d4\u05db\u05e8\u05d5\u05de\u05d8\u05d9\u05d3\u05d5\u05ea \u05e2\u05d3\u05d9\u05d9\u05df \u05e6\u05de\u05d5\u05d3\u05d5\u05ea \u05d6\u05d5 \u05dc\u05d6\u05d5, \u05d9\u05e9 \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05db\u05d0\u05dc\u05d4 \u05d1\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05e9\u05dc \u05db\u05dc <a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?page_id=44#44\">\u05db\u05e8\u05d5\u05de\u05d8\u05d9\u05d3\u05d4<\/a>, \u05db\u05dc\u05d5\u05de\u05e8 \u05de\u05e9\u05e0\u05d9 \u05e6\u05d9\u05d3\u05d9 \u05d4\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05dd. \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05d0\u05dc\u05d4 \u05d9\u05db\u05d5\u05dc\u05d9\u05dd \u05dc\u05d4\u05d9\u05e7\u05e9\u05e8 \u05dc\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8, \u05d5\u05d1\u05de\u05e7\u05d1\u05d9\u05dc \u05dc\u05d4\u05d9\u05e7\u05e9\u05e8 \u05dc\u05d7\u05d5\u05d8 \u05db\u05d9\u05e9\u05d5\u05e8. \u05dc\u05db\u05df \u05d1\u05d3\u05e8\u05da \u05db\u05dc\u05dc \u05d9\u05d4\u05d9\u05d4 \u05e7\u05d9\u05e9\u05d5\u05e8 \u05e9\u05dc \u05e9\u05e0\u05d9 <a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?page_id=44#30\">\u05d7\u05d5\u05d8\u05d9 \u05db\u05d9\u05e9\u05d5\u05e8<\/a> \u05dc\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05dd, \u05d0\u05d7\u05d3 \u05de\u05db\u05dc \u05e6\u05d3.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"size-full wp-image-497 aligncenter\" src=\"https:\/\/stwww1.weizmann.ac.il\/cell\/wp-content\/uploads\/sites\/17\/2016\/11\/kinetochore.jpg\" alt=\"\u05d0\u05d6\u05d5\u05e8 \u05d4\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05dc\u05d0\u05d7\u05e8 \u05d4\u05e7\u05d9\u05e9\u05d5\u05e8 \u05e9\u05dc \u05d7\u05d5\u05d8\u05d9 \u05d4\u05db\u05d9\u05e9\u05d5\u05e8\" width=\"250\" height=\"239\" \/><\/p>\n<p style=\"background-color: #f0f3ef\">\u05d6\u05db\u05d5\u05d9\u05d5\u05ea: Reprinted from Cell, vol 112, Don W. Cleveland et al. (2003), Centromeres and Kinetochores: From Epigenetics to Mitotic Checkpoint Signaling, p. 407-421 , \u00a9 2004, with permission from Elsevier.<\/p>\n<p>\u05d0\u05d6\u05d5\u05e8 \u05d4\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05dc\u05d0\u05d7\u05e8 \u05d4\u05e7\u05d9\u05e9\u05d5\u05e8 \u05e9\u05dc \u05d7\u05d5\u05d8\u05d9 \u05d4\u05db\u05d9\u05e9\u05d5\u05e8. \u05de\u05e9\u05de\u05d0\u05dc \u05d0\u05e4\u05e9\u05e8 \u05dc\u05e8\u05d0\u05d5\u05ea \u05d0\u05ea \u05d0\u05d6\u05d5\u05e8 \u05d4\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05db\u05e4\u05d9 \u05e9\u05d4\u05d5\u05d0 \u05e0\u05e8\u05d0\u05d4 \u05d1\u05de\u05d9\u05e7\u05e8\u05d5\u05e1\u05e7\u05d5\u05e4 \u05d0\u05dc\u05e7\u05d8\u05e8\u05d5\u05e0\u05d9\u05dd. \u05de\u05d9\u05de\u05d9\u05df, \u05e1\u05d5\u05de\u05e0\u05d5 \u05d1\u05e6\u05d1\u05e2 \u05d4\u05d0\u05d6\u05d5\u05e8\u05d9\u05dd \u05d5\u05d4\u05de\u05e8\u05db\u05d9\u05d1\u05d9\u05dd \u05d4\u05e2\u05d9\u05e7\u05e8\u05d9\u05d9\u05dd \u05e9\u05dc \u05d0\u05d6\u05d5\u05e8 \u05d6\u05d4.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u05d0\u05d9\u05da \u05d1\u05db\u05dc\u05dc \u05e0\u05e7\u05e9\u05e8\u05d9\u05dd \u05d7\u05d5\u05d8\u05d9 \u05d4\u05db\u05d9\u05e9\u05d5\u05e8 \u05dc\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05de\u05d9\u05dd? \u05d1\u05d0\u05d6\u05d5\u05e8 \u05d4\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05e0\u05de\u05e6\u05d0\u05d9\u05dd \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05d9\u05d9\u05d7\u05d5\u05d3\u05d9\u05d9\u05dd \u05e9\u05e0\u05e7\u05e9\u05e8\u05d9\u05dd \u05d1\u05de\u05d9\u05d5\u05d7\u05d3 \u05dc\u05d0\u05d6\u05d5\u05e8 \u05d6\u05d4 \u05d1\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05dd. \u05d1\u05e9\u05dc\u05d1\u05d9\u05dd \u05e9\u05d1\u05d4\u05dd \u05d4\u05db\u05e8\u05d5\u05de\u05d8\u05d9\u05d3\u05d5\u05ea \u05e2\u05d3\u05d9\u05d9\u05df \u05e6\u05de\u05d5\u05d3\u05d5\u05ea \u05d6\u05d5 \u05dc\u05d6\u05d5, \u05d9\u05e9 \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05db\u05d0\u05dc\u05d4 \u05d1\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8 \u05e9\u05dc \u05db\u05dc \u05db\u05e8\u05d5\u05de\u05d8\u05d9\u05d3\u05d4, \u05db\u05dc\u05d5\u05de\u05e8 \u05de\u05e9\u05e0\u05d9 \u05e6\u05d9\u05d3\u05d9 \u05d4\u05db\u05e8\u05d5\u05de\u05d5\u05d6\u05d5\u05dd. \u05d7\u05dc\u05d1\u05d5\u05e0\u05d9\u05dd \u05d0\u05dc\u05d4 \u05d9\u05db\u05d5\u05dc\u05d9\u05dd \u05dc\u05d4\u05d9\u05e7\u05e9\u05e8 \u05dc\u05e6\u05e0\u05d8\u05e8\u05d5\u05de\u05e8, \u05d5\u05d1\u05de\u05e7\u05d1\u05d9\u05dc &hellip; <a href=\"https:\/\/stwww1.weizmann.ac.il\/cell\/?p=496\">\u05dc\u05d4\u05de\u05e9\u05da \u05e7\u05e8\u05d9\u05d0\u05d4  <span class=\"meta-nav\">&larr;<\/span><\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[48],"tags":[],"class_list":["post-496","post","type-post","status-publish","format-standard","hentry","category-48"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/posts\/496"}],"collection":[{"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=496"}],"version-history":[{"count":3,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/posts\/496\/revisions"}],"predecessor-version":[{"id":834,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=\/wp\/v2\/posts\/496\/revisions\/834"}],"wp:attachment":[{"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=496"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=496"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/stwww1.weizmann.ac.il\/cell\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=496"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}