{"id":350,"date":"2016-08-16T11:56:02","date_gmt":"2016-08-16T08:56:02","guid":{"rendered":"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/?page_id=350"},"modified":"2016-08-16T11:56:02","modified_gmt":"2016-08-16T08:56:02","slug":"blast-explanation-en","status":"publish","type":"page","link":"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/blast-explanation-en\/","title":{"rendered":"BLAST"},"content":{"rendered":"<p style=\"direction: ltr\"><a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;Blast&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Blast &ndash; &#1514;&#1493;&#1499;&#1504;&#1514; &#1502;&#1495;&#1513;&#1489; &#1513;&#1497;&#1513; &#1500;&#1492; &#1488;&#1514; &#1492;&#1497;&#1499;&#1493;&#1500;&#1514; &#1500;&#1492;&#1513;&#1493;&#1493;&#1514; &#1489;&#1497;&#1503; &#1512;&#1510;&#1508;&#1497;&#1501;. &#1489;&#1488;&#1502;&#1510;&#1506;&#1493;&#1514; &#1514;&#1493;&#1499;&#1504;&#1492; &#1494;&#1493; &#1504;&#1497;&#1514;&#1503; &#1500;&#1494;&#1492;&#1493;&#1514; &#1500;&#1502;&#1513;&#1500; &#1490;&#1504;&#1497;&#1501; &#1492;&#1493;&#1502;&#1493;&#1500;&#1493;&#1490;&#1497;&#1501; (&#1489;&#1506;&#1500;&#1497; &#1512;&#1510;&#1507; &#1491;&#1493;&#1502;&#1492;) &#1489;&#1497;&#1510;&#1493;&#1512;&#1497;&#1501; &#1513;&#1493;&#1504;&#1497;&#1501; &#1499;&#1502;&#1493; &#1488;&#1491;&#1501;, &#1494;&#1489;&#1493;&#1489; &#1508;&#1497;&#1512;&#1493;&#1514; &#1488;&#1493; &#1514;&#1493;&#1500;&#1506;&#1514;, &#1500;&#1495;&#1508;&#1513; &#1512;&#1510;&#1507; &#1489;&#1500;&#1514;&#1497; &#1497;&#1491;&#1493;&#1506; &#1489;&#1502;&#1488;&#1490;&#1512; &#1499;&#1500; &#1492;&#1512;&#1510;&#1508;&#1497;&#1501; &#1513;&#1500; &#1492;&#1490;&#1504;&#1493;&#1501;, &#1493;&#1506;&#1493;&#1491;.&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/blast\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>BLAST<\/a> (<strong>B<\/strong>asic <strong>L<\/strong>ocal <strong>A<\/strong>lignment <strong>S<\/strong>earch <strong>T<\/strong>ool), is a sequence alignments tool, which provides a powerful way to compare novel sequences with previously characterized genes. <a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;Blast&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Blast &ndash; &#1514;&#1493;&#1499;&#1504;&#1514; &#1502;&#1495;&#1513;&#1489; &#1513;&#1497;&#1513; &#1500;&#1492; &#1488;&#1514; &#1492;&#1497;&#1499;&#1493;&#1500;&#1514; &#1500;&#1492;&#1513;&#1493;&#1493;&#1514; &#1489;&#1497;&#1503; &#1512;&#1510;&#1508;&#1497;&#1501;. &#1489;&#1488;&#1502;&#1510;&#1506;&#1493;&#1514; &#1514;&#1493;&#1499;&#1504;&#1492; &#1494;&#1493; &#1504;&#1497;&#1514;&#1503; &#1500;&#1494;&#1492;&#1493;&#1514; &#1500;&#1502;&#1513;&#1500; &#1490;&#1504;&#1497;&#1501; &#1492;&#1493;&#1502;&#1493;&#1500;&#1493;&#1490;&#1497;&#1501; (&#1489;&#1506;&#1500;&#1497; &#1512;&#1510;&#1507; &#1491;&#1493;&#1502;&#1492;) &#1489;&#1497;&#1510;&#1493;&#1512;&#1497;&#1501; &#1513;&#1493;&#1504;&#1497;&#1501; &#1499;&#1502;&#1493; &#1488;&#1491;&#1501;, &#1494;&#1489;&#1493;&#1489; &#1508;&#1497;&#1512;&#1493;&#1514; &#1488;&#1493; &#1514;&#1493;&#1500;&#1506;&#1514;, &#1500;&#1495;&#1508;&#1513; &#1512;&#1510;&#1507; &#1489;&#1500;&#1514;&#1497; &#1497;&#1491;&#1493;&#1506; &#1489;&#1502;&#1488;&#1490;&#1512; &#1499;&#1500; &#1492;&#1512;&#1510;&#1508;&#1497;&#1501; &#1513;&#1500; &#1492;&#1490;&#1504;&#1493;&#1501;, &#1493;&#1506;&#1493;&#1491;.&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/blast\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>BLAST<\/a> is a program that compares sequences in order to identify similarity between them. Using this program, a given sequence (the query sequence) can be compared with thousands of other sequences in international databases (blastn). The query sequence can also be compared with another given sequence (blast2seq). The databases contain information on nucleotides (<a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;DNA&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;DNA (&amp;lt;span dir=&amp;quot;ltr&amp;quot;&amp;gt;Deoxyribonucleic acid&amp;lt;\/span&amp;gt;) &ndash; &#1502;&#1493;&#1500;&#1511;&#1493;&#1500;&#1492; &#1513;&#1500; &#1495;&#1493;&#1502;&#1510;&#1514; &#1490;&#1512;&#1506;&#1497;&#1503; &#1492;&#1502;&#1488;&#1495;&#1505;&#1504;&#1514; &#1488;&#1514; &#1492;&#1502;&#1497;&#1491;&#1506; &#1492;&#1514;&#1493;&#1512;&#1513;&#1514;&#1497; &#1492;&#1495;&#1497;&#1493;&#1504;&#1497; &#1500;&#1502;&#1489;&#1504;&#1501; &#1493;&#1514;&#1508;&#1511;&#1493;&#1491;&#1501; &#1513;&#1500; &#1492;&#1497;&#1510;&#1493;&#1512;&#1497;&#1501; &#1493;&#1502;&#1488;&#1508;&#1513;&#1512;&#1514; &#1488;&#1514; &#1492;&#1506;&#1489;&#1512;&#1514;&#1493; &#1513;&#1500; &#1502;&#1497;&#1491;&#1506; &#1494;&#1492; &#1502;&#1491;&#1493;&#1512; &#1500;&#1491;&#1493;&#1512;. &#1502;&#1493;&#1500;&#1511;&#1493;&#1500;&#1492; &#1494;&#1493; &#1489;&#1504;&#1493;&#1497;&#1492; &#1502;&#1513;&#1504;&#1497; &#1490;&#1491;&#1497;&#1500;&#1497;&#1501; &#1502;&#1508;&#1493;&#1514;&#1500;&#1497;&#1501;. &#1499;&#1500; &#1490;&#1491;&#1497;&#1500; &#1489;&#1504;&#1493;&#1497; &#1502;&#1512;&#1510;&#1507; &#1513;&#1500; &#1504;&#1493;&#1511;&#1500;&#1488;&#1493;&#1496;&#1497;&#1491;&#1497;&#1501;. &#1492;&#1490;&#1491;&#1497;&#1500;&#1497;&#1501; &#1502;&#1493;&#1495;&#1494;&#1511;&#1497;&#1501; &#1497;&#1495;&#1491; &#1506;&#1500; &#1497;&#1491;&#1497; &#1511;&#1513;&#1512;&#1497;&#1501; &#1495;&#1500;&#1513;&#1497;&#1501; &#1489;&#1497;&#1503; &#1494;&#1493;&#1490;&#1493;&#1514; &#1492;&#1489;&#1505;&#1497;&#1505;&#1497;&#1501; &#1489;&#1504;&#1493;&#1511;&#1500;&#1488;&#1493;&#1496;&#1497;&#1491;&#1497;&#1501;. &#1488;&#1512;&#1489;&#1506;&#1514; &#1492;&#1504;&#1493;&#1511;&#1500;&#1488;&#1493;&#1496;&#1497;&#1491;&#1497;&#1501; &#1492;&#1502;&#1512;&#1499;&#1497;&#1489;&#1497;&#1501; &#1488;&#1514; &#1492;-DNA &#1502;&#1499;&#1497;&#1500;&#1497;&#1501; &#1488;&#1514; &#1492;&#1489;&#1505;&#1497;&#1505;&#1497;&#1501; (A) &#1488;&#1491;&#1504;&#1497;&#1503;, (C) &#1510;&#1497;&#1496;&#1493;&#1494;&#1497;&#1503;, (G) &#1490;&#1493;&#1488;&#1504;&#1497;&#1503;, (T) &#1496;&#1497;&#1502;&#1497;&#1503;. &#1494;&#1493;&#1490;&#1493;&#1514; &#1489;&#1505;&#1497;&#1505;&#1497;&#1501; &#1497;&#1499;&#1493;&#1500;&#1497;&#1501; &#1500;&#1492;&#1493;&#1493;&#1510;&#1512; &#1512;&#1511; &#1489;&#1497;&#1503; A &#1493;-T &#1493;&#1489;&#1497;&#1503; G &#1493;-C, &#1500;&#1499;&#1503; &#1512;&#1510;&#1507; &#1492;&#1489;&#1505;&#1497;&#1505;&#1497;&#1501; &#1489;&#1499;&#1500; &#1488;&#1495;&#1491; &#1502;&#1492;&#1490;&#1491;&#1497;&#1500;&#1497;&#1501; &#1504;&#1490;&#1494;&#1512; &#1502;&#1489;&#1503; &#1494;&#1493;&#1490;&#1493;. &#1502;&#1493;&#1500;&#1511;&#1493;&#1500;&#1493;&#1514; &#1492;-DNA &#1502;&#1488;&#1493;&#1512;&#1490;&#1504;&#1493;&#1514; &#1489;&#1499;&#1512;&#1493;&#1502;&#1493;&#1494;&#1493;&#1502;&#1497;&#1501;.&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/dna\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>DNA<\/a>, <a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;RNA&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;RNA (&amp;lt;span dir=&amp;quot;ltr&amp;quot;&amp;gt;Ribonucleic acid&amp;lt;\/span&amp;gt;) &ndash; &#1495;&#1493;&#1502;&#1510;&#1514; &#1490;&#1512;&#1506;&#1497;&#1503; &#1492;&#1504;&#1489;&#1504;&#1497;&#1514; &#1506;&#1500; &#1490;&#1489;&#1497; &#1514;&#1489;&#1504;&#1497;&#1514; &#1513;&#1500; DNA &#1493;&#1502;&#1492;&#1493;&#1493;&#1492; &#1514;&#1506;&#1514;&#1497;&#1511; &#1513;&#1500;&#1493;, &#1495;&#1493;&#1502;&#1510;&#1514; &#1490;&#1512;&#1506;&#1497;&#1503; &#1494;&#1493; &#1502;&#1493;&#1512;&#1499;&#1489;&#1514; &#1502;&#1508;&#1493;&#1500;&#1497;&#1502;&#1512; &#1513;&#1500; &#1504;&#1493;&#1511;&#1500;&#1497;&#1488;&#1493;&#1496;&#1497;&#1491;&#1497;&#1501; &#1492;&#1502;&#1499;&#1497;&#1500;&#1497;&#1501; &#1505;&#1493;&#1499;&#1512; &#1502;&#1505;&#1493;&#1490; &#1512;&#1497;&#1489;&#1493;&#1494; &#1493;&#1489;&#1505;&#1497;&#1505; &#1495;&#1504;&#1511;&#1504;&#1497; &#1488;&#1493;&#1512;&#1510;&#1497;&#1500;(U) (&#1489;&#1502;&#1511;&#1493;&#1501; &#1496;&#1497;&#1502;&#1497;&#1503; (T) &#1492;&#1502;&#1493;&#1508;&#1497;&#1506; &#1489;- DNA ). &#1502;&#1493;&#1499;&#1512;&#1493;&#1514; &#1502;&#1505;&#1508;&#1512; &#1511;&#1489;&#1493;&#1510;&#1493;&#1514; &#1513;&#1500; &#1502;&#1493;&#1500;&#1511;&#1493;&#1500;&#1514; RNA : RNA-&#1513;&#1500;&#1497;&#1495; (&amp;lt;span dir=&amp;quot;ltr&amp;quot;&amp;gt;mRNA&amp;lt;\/span&amp;gt;), RNA-&#1502;&#1493;&#1489;&#1497;&#1500; (&amp;lt;span dir=&amp;quot;ltr&amp;quot;&amp;gt;tRNA&amp;lt;\/span&amp;gt;), RNA-&#1512;&#1497;&#1489;&#1493;&#1494;&#1493;&#1502;&#1500;&#1497; (rRNA).&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/rna\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>RNA<\/a>) or proteins. Any scientist identifying a new sequence forwards it to the databases, so that the databases are constantly being updated. <a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;Blast&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Blast &ndash; &#1514;&#1493;&#1499;&#1504;&#1514; &#1502;&#1495;&#1513;&#1489; &#1513;&#1497;&#1513; &#1500;&#1492; &#1488;&#1514; &#1492;&#1497;&#1499;&#1493;&#1500;&#1514; &#1500;&#1492;&#1513;&#1493;&#1493;&#1514; &#1489;&#1497;&#1503; &#1512;&#1510;&#1508;&#1497;&#1501;. &#1489;&#1488;&#1502;&#1510;&#1506;&#1493;&#1514; &#1514;&#1493;&#1499;&#1504;&#1492; &#1494;&#1493; &#1504;&#1497;&#1514;&#1503; &#1500;&#1494;&#1492;&#1493;&#1514; &#1500;&#1502;&#1513;&#1500; &#1490;&#1504;&#1497;&#1501; &#1492;&#1493;&#1502;&#1493;&#1500;&#1493;&#1490;&#1497;&#1501; (&#1489;&#1506;&#1500;&#1497; &#1512;&#1510;&#1507; &#1491;&#1493;&#1502;&#1492;) &#1489;&#1497;&#1510;&#1493;&#1512;&#1497;&#1501; &#1513;&#1493;&#1504;&#1497;&#1501; &#1499;&#1502;&#1493; &#1488;&#1491;&#1501;, &#1494;&#1489;&#1493;&#1489; &#1508;&#1497;&#1512;&#1493;&#1514; &#1488;&#1493; &#1514;&#1493;&#1500;&#1506;&#1514;, &#1500;&#1495;&#1508;&#1513; &#1512;&#1510;&#1507; &#1489;&#1500;&#1514;&#1497; &#1497;&#1491;&#1493;&#1506; &#1489;&#1502;&#1488;&#1490;&#1512; &#1499;&#1500; &#1492;&#1512;&#1510;&#1508;&#1497;&#1501; &#1513;&#1500; &#1492;&#1490;&#1504;&#1493;&#1501;, &#1493;&#1506;&#1493;&#1491;.&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/blast\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>BLAST<\/a> was developed by the NCBI and is accessible to the public on the Internet. <a class=\"glossaryLink\"  aria-describedby=\"tt\"  data-cmtooltip=\"&lt;div class=glossaryItemTitle&gt;Blast&lt;span class=&amp;quot;dashicons &amp;quot; data-icon=&amp;quot;&amp;quot; style=&amp;quot;color:#000;display:inline;vertical-align:baseline;&amp;quot;&gt;&lt;\/span&gt;&lt;\/div&gt;&lt;div class=glossaryItemBody&gt;Blast &ndash; &#1514;&#1493;&#1499;&#1504;&#1514; &#1502;&#1495;&#1513;&#1489; &#1513;&#1497;&#1513; &#1500;&#1492; &#1488;&#1514; &#1492;&#1497;&#1499;&#1493;&#1500;&#1514; &#1500;&#1492;&#1513;&#1493;&#1493;&#1514; &#1489;&#1497;&#1503; &#1512;&#1510;&#1508;&#1497;&#1501;. &#1489;&#1488;&#1502;&#1510;&#1506;&#1493;&#1514; &#1514;&#1493;&#1499;&#1504;&#1492; &#1494;&#1493; &#1504;&#1497;&#1514;&#1503; &#1500;&#1494;&#1492;&#1493;&#1514; &#1500;&#1502;&#1513;&#1500; &#1490;&#1504;&#1497;&#1501; &#1492;&#1493;&#1502;&#1493;&#1500;&#1493;&#1490;&#1497;&#1501; (&#1489;&#1506;&#1500;&#1497; &#1512;&#1510;&#1507; &#1491;&#1493;&#1502;&#1492;) &#1489;&#1497;&#1510;&#1493;&#1512;&#1497;&#1501; &#1513;&#1493;&#1504;&#1497;&#1501; &#1499;&#1502;&#1493; &#1488;&#1491;&#1501;, &#1494;&#1489;&#1493;&#1489; &#1508;&#1497;&#1512;&#1493;&#1514; &#1488;&#1493; &#1514;&#1493;&#1500;&#1506;&#1514;, &#1500;&#1495;&#1508;&#1513; &#1512;&#1510;&#1507; &#1489;&#1500;&#1514;&#1497; &#1497;&#1491;&#1493;&#1506; &#1489;&#1502;&#1488;&#1490;&#1512; &#1499;&#1500; &#1492;&#1512;&#1510;&#1508;&#1497;&#1501; &#1513;&#1500; &#1492;&#1490;&#1504;&#1493;&#1501;, &#1493;&#1506;&#1493;&#1491;.&lt;\/div&gt;\"  href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/glossary\/blast\/\"  data-gt-translate-attributes='[{\"attribute\":\"data-cmtooltip\", \"format\":\"html\"}]'>BLAST<\/a> was developed by the NCBI and is accessible to the public on the Internet.<\/p>","protected":false},"excerpt":{"rendered":"<p>BLAST (Basic Local Alignment Search Tool), is a sequence alignments tool, which provides a powerful way to compare novel sequences with previously characterized genes. BLAST is a program that compares sequences in order to identify similarity between them. Using this &hellip; <a href=\"https:\/\/stwww1.weizmann.ac.il\/bioinformatics\/blast-explanation-en\/\">\u05dc\u05d4\u05de\u05e9\u05da \u05e7\u05e8\u05d9\u05d0\u05d4  <span class=\"meta-nav\">&larr;<\/span><\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-350","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t<!-- All in One SEO 4.9.9 - aioseo.com -->\n\t<meta name=\"description\" content=\"BLAST (Basic Local Alignment Search Tool), is a sequence alignments tool, which provides a powerful way to compare novel sequences with previously characterized genes. 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